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Cardiac arrest

Double sequential defibrillation shows no benefit

Implementation of double sequential defibrillation (DSD): an Aotearoa New Zealand observational study
Resuscitation · Added 23 August 2026

NZ EMS observational study (n=1,401) found no survival benefit after DSD implementation for refractory VF/VT, with lower ROSC odds in DSD patients likely reflecting confounding by indication.

Study type
Cohort
Design
Retrospective pre/post observational cohort
Participants
1,401 patients with refractory VF/VT (pre 663, post 738)
Main finding
No significant difference in ROSC or 30-day survival after DSD implementation; DSD patients had lower odds of ROSC (aOR 0.59, 95% CI 0.41-0.85) and late-DSD aOR 0.46 (95% CI 0.30-0.71).
Caveat
Confounding by indication — DSD used in patients with poorest prognosis
Bottom line
Supports current practice

Why it matters in Australia (Medium relevance). Australasian context relevant to services using DSD, but findings may be confounded and timing guidance remains unclear.

Learning goal

Weigh the benefits and harms of double sequential defibrillation for refractory ventricular fibrillation in cardiac arrest.

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