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Sepsis intubations: haemodynamic trouble common

Characteristics, Practice Patterns, and Outcomes of Emergency Department Intubation for Sepsis: An ANZEDAR Registry Study
Emergency Medicine Australasia · 2026-10 · Added 9 October 2026

A retrospective analysis of the ANZEDAR registry (79 hospitals, 2010–26) covering 280 sepsis intubations found haemodynamic complications in 27.9% and peri-intubation cardiac arrest in 4.6%, with less waveform capnography use than non-sepsis intubations.

Study type

Registry

Design

Retrospective analysis of a prospective multi-centre registry

Participants

280 sepsis intubations of 11,289 registry intubations (30 paediatric)

Main finding

2.5% of all ED intubations were for sepsis; haemodynamic complications 27.9% and peri-intubation cardiac arrest 4.6%; waveform capnography 87.5% vs 94.1% in non-sepsis (p<0.001); laryngoscopic view and first-pass success comparable to non-sepsis

Caveat

ED-based registry of in-hospital intubations by ED and anaesthetic staff, not prehospital crews

Bottom line

Context only

Learning goal

Weigh the haemodynamic risks of intubating septic patients and refine my resuscitation strategy before drug-assisted intubation.

More

• Topic: Sepsis & infection
• Daily scan: 9 October 2026

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