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Home Cardiac arrest Unwitnessed arrests: mostly women, mostly at home

Cardiac arrest

Unwitnessed arrests: mostly women, mostly at home

Determinants of unwitnessed out-of-hospital cardiac arrest: a systematic review (HL-D-26-00618)
Heart & Lung · 2026-10-08 · Added 10 October 2026

A systematic review of 22 studies (210,028 people) found female sex and arrest at home were the most consistent determinants of unwitnessed OHCA, with weaker, mostly unadjusted evidence for night or sleep arrests, deprivation and psychiatric illness.

Study type
Systematic review
Design
Systematic review
Participants
22 studies, 210,028 adults
Main finding
Female sex and home location most consistently associated with unwitnessed arrest; limited evidence for arrests at night or during sleep, low socioeconomic status, type I diabetes and psychiatric illness
Caveat
Much of the included evidence came from unadjusted analyses with heterogeneous definitions of witnessed status
Bottom line
Context only

Why it matters in Australia (High relevance). The determinants are population and household factors, not features of a particular EMS system, so the pattern travels directly to Australian communities.

Learning goal

Recognise which patients are most likely to sustain an unwitnessed cardiac arrest and how this shapes response priorities.

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