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Cardiac arrest

Two-thirds of ECPR survivors alive at five years

Long-Term Survival Following Extracorporeal Cardiopulmonary Resuscitation: A Two-Center Five-Year Analysis
Resuscitation · 2026-11 · Added 4 November 2026

A US–Czech retrospective cohort of 728 patients given ECPR for refractory VT/VF OHCA found 29% survived to hospital discharge and, among those survivors, about two-thirds were still alive at five years with favourable cerebral performance in most.

Study type
Cohort
Design
Retrospective two-centre cohort (Minnesota, USA and Prague, Czechia)
Participants
728 ECPR patients, 211 discharged alive
Main finding
211/728 (29.0%) survived to discharge; 76.9% and 67.2% of hospital survivors were alive at 1 and 5 years; CPC 1–2 in 78.7% at discharge and above 93% among survivors beyond 1 year; five-year survival ranged from 91.6% (18–39 years) to 52.9% (>70 years)
Caveat
Highly selected patients within established ECPR systems, no control group, and most deaths clustered in the first 90 days after discharge
Bottom line
Context only

Why it matters in Australia (Medium relevance). ECPR-capable centres are scarce in Australia, so this informs destination decisions and which refractory arrests are worth a fast transport rather than anything crews do on scene.

Learning goal

Weigh the role of ECPR eligibility criteria in improving long-term outcomes for patients in refractory out-of-hospital cardiac arrest.

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