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Cardiac arrest

Longer collapse-to-contact times linked with ROSC

Longer collapse-to-first-medical-contact interval is independently associated with ROSC in out-of-hospital cardiac arrest: a paradoxical finding that may reflect case-mix differences
Frontiers in Medicine · 2026-10-27 · Added 12 November 2026

A Chinese single-centre retrospective cohort of 152 OHCA cases found longer collapse-to-first-medical-contact intervals were independently associated with prehospital ROSC — a paradox the authors attribute to case-mix differences rather than a real benefit of slower response.

Study type
Cohort
Design
Retrospective cohort with dispatch-log and onboard timestamps
Participants
152 consecutive OHCA patients, single emergency centre
Main finding
Longer collapse-to-first-medical-contact interval was independently associated with prehospital ROSC; the authors attribute the paradoxical direction to case-mix differences (arrest aetiology, shockable rhythm)
Caveat
Small single-centre cohort where sicker patients reaching crews faster likely explains the association
Bottom line
Hypothesis-generating

Why it matters in Australia (Medium relevance). Response-interval questions are core to any ambulance service, but this is a small single-centre Chinese system with case-mix confounding the authors themselves flag.

Learning goal

Weigh how case-mix differences shape my interpretation of response interval data when judging cardiac arrest outcomes.

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