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US statewide protocols for prehospital blood vary

Statewide Emergency Medical Services Protocols for Field-Initiated Blood Resuscitation
Prehospital Emergency Care · Added 26 April 2026

Study type
Cross-sectional
Design
Cross-sectional review of publicly available statewide EMS protocols
Participants
32 statewide protocols (31 states plus DC)
Main finding
13 of 32 (42%) protocols allowed field-initiated blood transfusion; all allowed trauma use, 69% allowed medical use, 69% allowed paediatric transfusion, 23% specified low titer O whole blood, and only 31% addressed biologically female patients
Caveat
US protocols only; descriptive, not linked to patient outcomes, and excludes critical care/interfacility protocols
Bottom line
Context only

Learning goal

Compare protocol variations in prehospital blood transfusion to refine my judgement on patient selection.

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