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Quantra sonorheometry rules out trauma coagulopathy

Sonorheometry to detect traumatic induced coagulopathy during initial management of trauma patients: an observational, multi-center study
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine · Added 22 April 2026

Tested whether Quantra can rapidly detect trauma-induced coagulopathy against standard lab tests, and found early Quantra analysis may reliably exclude TIC, but prospective validation is still needed.

Study type

Cohort

Design

Multicentre observational diagnostic accuracy study at four level-1 trauma centres

Participants

504 severe trauma patients >16 years (285 derivation, 219 validation)

Main finding

AUCs 0.82–0.91 for detecting TIC thresholds; in validation, negative predictive values 0.88–1.00 but positive predictive values only 0.13–0.67

Caveat

In-hospital testing at level-1 trauma centres, not prehospital; low PPV and prospective validation still required

Bottom line

Hypothesis-generating

Learning goal

Weigh how rapid point-of-care coagulometry informs my decision to transfuse trauma patients before coagulopathy is confirmed.

More

• Topic: Trauma
• Daily scan: 22 April 2026

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