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Cardiac arrest
ECPR for OHCA: pump the brakes
Rapid Transport to Extracorporeal CPR: Urging Caution Prior to Implementation
Prehospital Emergency Care · 2026-10-22 · Added 25 October 2026
A Prehospital Emergency Care commentary reviewing the ARREST, INCEPTION and Prague OHCA trials argues the ECPR evidence is not strong enough for widespread prehospital adoption, because any benefit cannot be separated from the effect of the intra-arrest transport ECPR programs require.
- Study type
- Other
- Design
- Narrative review/commentary of three randomised ECPR trials
- Participants
- Three RCTs (ARREST n=30, INCEPTION, Prague OHCA)
- Main finding
- Only ARREST (30 patients) strongly favoured ECPR; INCEPTION and Prague OHCA were not statistically significant, and the authors argue intra-arrest transport effects cannot be excluded as a driver of reported benefit
- Caveat
- A commentary, not new data — interpretation of already-published trials
- Bottom line
- Context only
Why it matters in Australia (Medium relevance). ECPR for OHCA depends on coordinated intra-arrest transport, so the implementation decision sits with ambulance systems here too; no Australian service runs routine ECPR for arrest, and this is a useful framing piece before anyone is asked to build one.
Learning goal
Weigh the benefits and harms of intra-arrest transport for extracorporeal CPR candidacy in refractory out-of-hospital cardiac arrest.
More
- Topic: Cardiac arrest
- Daily scan: 25 October 2026
- Podcast: Paramedic Papers Daily, 25 October 2026
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ECPR timing in refractory OHCA: survival gap persists
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Hot nights linked to more OHCA
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Pad application is the AED time bottleneck
Timestamps from 8,115 remotely monitored Japanese AEDs showed pad application consumed a median 81% of the power-on-to-first-analysis interval, with completion inside about 50 seconds marking shocks delivered within 60 seconds of power-on.
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Dispatcher training + volunteer app: more CPR, no outcome gain
A stepped-wedge cluster-randomised trial in French EMS agencies found dispatcher training in arrest recognition, telephone CPR and a geolocated volunteer responder app was associated with more bystander CPR (61.4% to 70.9%, adjusted OR 1.54), an effect that lost significance after adjusting for secular trends; clinical outcomes did not improve.