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Cardiac arrest

ECPR for OHCA: pump the brakes

Rapid Transport to Extracorporeal CPR: Urging Caution Prior to Implementation
Prehospital Emergency Care · 2026-10-22 · Added 25 October 2026

A Prehospital Emergency Care commentary reviewing the ARREST, INCEPTION and Prague OHCA trials argues the ECPR evidence is not strong enough for widespread prehospital adoption, because any benefit cannot be separated from the effect of the intra-arrest transport ECPR programs require.

Study type
Other
Design
Narrative review/commentary of three randomised ECPR trials
Participants
Three RCTs (ARREST n=30, INCEPTION, Prague OHCA)
Main finding
Only ARREST (30 patients) strongly favoured ECPR; INCEPTION and Prague OHCA were not statistically significant, and the authors argue intra-arrest transport effects cannot be excluded as a driver of reported benefit
Caveat
A commentary, not new data — interpretation of already-published trials
Bottom line
Context only

Why it matters in Australia (Medium relevance). ECPR for OHCA depends on coordinated intra-arrest transport, so the implementation decision sits with ambulance systems here too; no Australian service runs routine ECPR for arrest, and this is a useful framing piece before anyone is asked to build one.

Learning goal

Weigh the benefits and harms of intra-arrest transport for extracorporeal CPR candidacy in refractory out-of-hospital cardiac arrest.

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