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Cardiac (non-arrest)

Roadside capillary troponin for chest pain

Diagnostic accuracy of prehospital capillary high-sensitivity cardiac troponin I in patients with acute chest pain: the prospective multicenter VALIDATE study
European Journal of Emergency Medicine · 2026-11-10 · Added 11 November 2026

A French prospective multicentre diagnostic accuracy study (VALIDATE) tested prehospital capillary high-sensitivity troponin I on a point-of-care device against NSTEMI at hospital discharge in adults with acute chest pain, with treating clinicians blinded to results.

Study type
Cross-sectional
Design
Prospective multicentre diagnostic accuracy study, blinded index test (physician-staffed)
Participants
Adults with acute chest pain across 4 French EMS systems and 10 mobile intensive care units
Main finding
Diagnostic performance expressed as AUC with 95% CIs against predefined thresholds; the indexed abstract's main-results section carries no numbers
Caveat
Physician-staffed French setting and no numeric results in the indexed abstract
Bottom line
Hypothesis-generating

Why it matters in Australia (Medium relevance). Point-of-care troponin isn't something Australian ambulances carry — adoption would need a guideline change — and the French systems that ran it are physician-staffed

Learning goal

Weigh the value of prehospital point-of-care troponin testing in my assessment of acute chest pain.

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