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Stroke & neuro

Ultrasound added to stroke scales for LVO triage

Added value of brain perfusion ultrasound to prehospital stroke scales-a secondary analysis of the SONAS trial
Frontiers in Neurology · 2026-10-23 · Added 9 November 2026

A German exploratory reanalysis of the 20-patient SONAS trial found portable non-imaging brain perfusion ultrasound combined with prehospital stroke scales sorted suspected stroke into likely-LVO, likely-non-LVO and unassessable groups better than either method alone.

Study type
Other
Design
Exploratory secondary analysis of a 20-patient portable ultrasound device trial
Participants
20 patients with acute ischaemic stroke
Main finding
Combining brain perfusion ultrasound with prehospital stroke scales shifted sensitivity and negative predictive value higher and reclassified all patients misdiagnosed by either method alone; three prehospital-ICH false positives showed severe perfusion deficits suggesting LVO
Caveat
Only 20 patients, retrospective design, and the authors themselves call validation critical
Bottom line
Hypothesis-generating

Why it matters in Australia (Medium relevance). Portable ultrasound is carried by a handful of Australian services, most don't, and prehospital LVO triage is an active question here — the approach informs that debate rather than current practice.

Learning goal

Weigh the value of portable brain perfusion ultrasound in improving prehospital triage of suspected large vessel occlusion stroke.

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