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Prehospital pulse pressure flags trauma bleeding

Pre-hospital pulse pressure as an early predictor of active hemorrhage in trauma patients
Injury · 2026-10-15 · Added 26 October 2026

A retrospective study of 2,177 adult trauma patients across three Canadian level 1 trauma centres found prehospital pulse pressure predicted active haemorrhage (AUC 0.73), with each 10 mmHg narrowing raising the odds by 51% and a cut-off of ≤45 mmHg most useful for ruling bleeding out.

Study type
Cohort
Design
Retrospective multicentre cohort
Participants
2,177 adult trauma patients (68 with active haemorrhage)
Main finding
Prehospital pulse pressure predicted active haemorrhage (AUC 0.73, similar to SBP 0.74); each 10 mmHg narrowing raised the odds by 51% (OR 1.51, 95% CI 1.28–1.79), and PP ≤45 mmHg was best for rule-out given high negative predictive value
Caveat
Retrospective design with only 68 bleeding patients, so the cut-off needs prospective validation
Bottom line
Hypothesis-generating

Why it matters in Australia (High relevance). Pulse pressure is just two numbers off the cuff you already take — no new equipment or drugs, so it applies to Australian practice as it stands. The outcome (transfusion or haemorrhage control) is hospital-side, but the flag is raised on scene.

Learning goal

Recognise narrowing pulse pressure as an early sign of haemorrhage in trauma patients before blood pressure falls.

Open in dashboard Read the paper (DOI) PubMed

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