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Cardiac arrest

Long resuscitations don't rule out good recovery

Time to Return of Spontaneous Circulation and Long-Term Outcomes in Bystander-Witnessed Out-of-Hospital Cardiac Arrest Survivors
Resuscitation · 2026-10 · Added 8 October 2026

Danish national registry study of bystander-witnessed OHCA survivors asking whether longer time-to-ROSC means worse long-term outcomes — anoxic brain damage rose with time, but long-term survival, return to work and nursing-home admission did not, showing prolonged resuscitation doesn't preclude good recovery.

Study type
Registry
Design
National registry cohort, stratified by time-to-ROSC
Participants
2,583 bystander-witnessed OHCA survivors (median age 65, median time-to-ROSC 14 min)
Main finding
Anoxic brain damage increased with time-to-ROSC (0.3%, 1.8% and 3.2% for 0-10, 11-18 and >18 min; adjusted HR 9.98 for >18 min vs 0-10 min), but 5-year survival (~79%), return to work (~60%) and nursing-home admission did not differ between groups
Caveat
Only patients surviving at least 30 days were included — early deaths are excluded, so this says nothing about whether longer efforts save more people overall
Bottom line
Supports current practice

Why it matters in Australia (High relevance). Speaks straight to the on-scene decision of how long to work an arrest — the 'good survivor after a long resus' question comes up on every crew in the country.

Learning goal

Strengthen my judgement on when prolonged resuscitation efforts remain worthwhile before declaring futility in cardiac arrest.

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