Home › Trauma › Calcium with prehospital blood products for trauma

Trauma

Calcium with prehospital blood products for trauma

Calcium during prehospital trauma blood-product resuscitation: A meta-analysis
The American Journal of Emergency Medicine · Added 25 September 2026

Meta-analysis of calcium supplementation during prehospital blood-product trauma resuscitation. Abstract not yet available (ahead-of-print).

Study type

Systematic review

Design

Systematic review and meta-analysis of nonrandomised comparative and prevalence studies

Participants

17 studies of adult trauma patients

Main finding

Calcium-exposed patients had lower hypocalcaemia (military cohort RR 0.40, 95% CI 0.27–0.61; civilian air-transport RR 0.51, 95% CI 0.32–0.82; exploratory pooled RR 0.45, 95% CI 0.33–0.61); hypocalcaemia was frequent after prehospital blood-product resuscitation

Caveat

Only two clinically dissimilar nonrandomised studies; threshold variation, uncertain sampling relative to in-hospital treatment and residual confounding preclude causal inference

Bottom line

Hypothesis-generating

Learning goal

Weigh the benefits and limitations of routine calcium supplementation during prehospital blood-product trauma resuscitation.

More

• Topic: Trauma
• Daily scan: 25 September 2026

Related papers on Trauma

• Prehospital minithoracostomy vs chest drain

  Prehospital Emergency Care · 29 Sep 2026 · Cohort · Hypothesis-generating

  Retrospective physician-led HEMS cohort (94 trauma patients) comparing prehospital minithoracostomy with chest drainage — minithoracostomy carried no meaningful scene-time penalty and fewer recorded complications, but non-random allocation and few events make it hypothesis-generating only.

• Traumatic arrest in older adults

  Resuscitation Plus · 22 Sep 2026 · Registry · Context only

  French national registry study of 5,595 traumatic cardiac arrests comparing older (≥65) with younger adults — older patients achieved ROSC more often (22.5% vs 18.6%) but 30-day survival was lower (0.5% vs 1.2%), leading the authors to argue age alone shouldn't preclude resuscitation though a concurrent medical cause should be sought

• Causal model for prehospital blood trials

  Prehospital Emergency Care · 22 Sep 2026 · Modelling · Context only

  Methodology paper building an expert-refined causal model for prehospital blood transfusion trials in traumatic haemorrhagic shock — maps confounders (system times, training, units available) and mediators so future studies can actually isolate a treatment effect against crystalloid

• Whole blood during prolonged entrapment rescue

  Prehospital Emergency Care · 22 Sep 2026 · Case series · Context only

  Case report of an entrapped trauma patient after a motor vehicle collision receiving advanced airway management, finger thoracostomies and multiple units of low-titre O-positive whole blood during a prolonged multi-agency extrication — the blood came via the regional prehospital program supporting a physician response team