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Cardiac arrest

Smaller bags worse for CPR ventilation

Bag size for manual ventilation during cardiopulmonary resuscitation in adult cardiac arrest: a systematic review
Resuscitation Plus · Added 9 August 2026

Systematic review testing whether smaller self-inflating bags improve CPR outcomes — they found limited very-low-certainty evidence suggesting smaller bags (450-700mL) were associated with lower survival with favourable neuro outcomes compared to standard adult bags (1000-1685mL).

Study type
Systematic review
Design
Systematic review (ILCOR Continuous Evidence Evaluation, GRADE)
Participants
One observational study of 1994 OHCA patients plus two simulation cross-over studies
Main finding
Smaller bags (450–700 mL) were associated with lower survival with favourable neurological outcome (AOR 0.65, 95% CI 0.43–0.99) and lower event survival (AOR 0.73, 95% CI 0.60–0.90) versus standard adult bags (1000–1685 mL); no randomised trials identified
Caveat
Very-low certainty evidence from a single before-and-after observational study and no randomised trials
Bottom line
Supports current practice

Why it matters in Australia (High relevance). Directly relevant to prehospital CPR practice — bag valve choice is a standard clinical decision and these findings challenge the assumption that smaller bags are safer for airway protection during CPR.

Learning goal

Update my choice of self-inflating bag size when ventilating adults in cardiac arrest.

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