Paramedic PapersHome Cardiac arrest No sex differences in OHCA with confirmed CAD
Cardiac arrest
No sex differences in OHCA with confirmed CAD
Sex differences in management and outcomes after out-of-hospital cardiac arrest with angiographically confirmed obstructive coronary artery disease
Resuscitation Plus · Added 29 September 2026
Post hoc analysis of a prospective European OHCA registry (2012–2023) testing whether sex-based differences in care persist when obstructive CAD is angiographically confirmed as the arrest cause — among 580 patients (15.3% women), PCI use, procedural success, targeted temperature management and ECPR were similar between sexes, 30-day survival was 66.2% in women vs 61.5% in men (p=0.33), favourable neurological outcome 55.1% vs 53.8% (p=0.82), and female sex was not independently associated with 30-day survival (adjusted OR 0.75, not significant).
- Study type
- Registry
- Design
- Post hoc analysis of a prospective European OHCA registry
- Participants
- 580 adults with OHCA and angiographically confirmed obstructive CAD (15.3% women)
- Main finding
- 30-day survival 66.2% (women) vs 61.5% (men), p=0.33; favourable neurological outcome 55.1% vs 53.8%, p=0.82; sex not associated with 30-day survival (adjusted OR 0.75, 95% CI 0.39–1.41).
- Caveat
- Post hoc analysis of a selected cohort with only 15.3% women; in-hospital subgroup of OHCA patients.
- Bottom line
- Context only
Why it matters in Australia (Medium relevance). Registry data on in-hospital post-ROSC care rather than a prehospital intervention — useful context for the post-arrest pathways ACTAS feeds into (CMG 4 Cardiac Arrest: Adult, CMG 16 Suspected ACS), but nothing changes on the road tomorrow.
Learning goal
Recognise how sex bias may delay recognition of obstructive coronary disease in women after out-of-hospital cardiac arrest.
More
- Topic: Cardiac arrest
- Daily scan: 29 September 2026
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