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Cardiac (non-arrest)

Aortic emergencies: HR/BP drugs in transport

Medical Management of Aortic Emergencies in Critical Care Transport
Prehospital Emergency Care · Added 22 September 2026

Cohort of 1,530 aortic emergencies in US critical care transport — esmolol, labetalol and nicardipine strategies hit HR/BP targets at similar rates, with esmolol alone showing the highest hypotension incidence (9.3%) and labetalol alone the lowest (2.1%)

Study type
Cohort
Design
Retrospective cohort of US critical care transport encounters
Participants
1,530 adults with aortic emergencies
Main finding
All drug strategies achieved target HR/SBP similarly; hypotension lowest with labetalol alone (2.1%) and highest with esmolol (9.3%); esmolol/nicardipine combination had lowest tachycardia (11.0%)
Caveat
Retrospective design; US critical care transport setting not directly applicable to Australian paramedic practice
Bottom line
Context only

Why it matters in Australia (Low relevance). transferability — critical-care transport scope built on infusions; beta-blockers aren't in the extracted ACTAS formulary (only QAS carries them interstate) — background awareness only

Learning goal

Weigh the hypotension risks of different heart rate and blood pressure control strategies in suspected aortic emergencies.

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