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Adrenaline given in only 60% of paediatric OHCA

Practice variability of epinephrine administration in pediatric out-of-hospital cardiac arrest in the United States
Resuscitation Plus · Added 29 August 2026

Retrospective analysis of US NEMSIS data found adrenaline was administered in only 60% of paediatric out-of-hospital cardiac arrests, with longer scene times, advanced airway attempts, and defibrillation associated with higher odds of administration, while public settings and female sex correlated with lower odds.

Study type
Registry
Design
Retrospective observational analysis of US NEMSIS 2021 registry data
Participants
8,495 paediatric OHCA events managed by ALS units
Main finding
40.2% of paediatric OHCA events received no adrenaline; administration associated with younger age, urban setting, scene time >10 min, advanced airway attempt (OR 8.33) and defibrillation (OR 1.95); lower odds in public settings (OR 0.55) and females (OR 0.83)
Caveat
Registry data reliant on documentation accuracy; associations do not establish causation
Bottom line
Context only

Why it matters in Australia (High relevance). Adrenaline is carried by ACTAS (AP scope) and paediatric cardiac arrest is within our scope—US practice patterns are directly relevant despite jurisdictional differences.

Learning goal

Recognise the system and setting factors that influence adrenaline administration in paediatric cardiac arrest.

Open in dashboard Read the paper (DOI) PubMed

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