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Airway & ventilation

Predictors of hyperoxaemia after prehospital oxygen

Independent predictors of hyperoxemia following prehospital oxygen therapy: A prospective cohort study
The American Journal of Emergency Medicine · Added 16 August 2026

Prospective cohort of 245 patients found 24.5% had hyperoxemia (PaO₂ >120 mmHg), with intubation (OR 38.89) and transport duration ≥24 min (OR 13.74) as independent predictors.

Study type
Cohort
Design
Prospective single-centre cohort
Participants
245 adults transported by ambulance receiving oxygen
Main finding
24.5% were hyperoxaemic (PaO2 >120 mmHg) on ED arrival; independent predictors were intubation (OR 38.89) and transport duration ≥24 min (OR 13.74); ED SpO2 ≥96.5% predicted hyperoxaemia with AUC 0.70
Caveat
Single-centre study at one tertiary ED, limiting generalisability
Bottom line
Hypothesis-generating

Why it matters in Australia (High relevance). Directly relevant to daily paramedic practice, clear actionable findings about oxygen titration and reassessment during transport.

Learning goal

Refine my titration of prehospital oxygen therapy to recognise and avoid hyperoxaemia, particularly in intubated patients.

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