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Adrenaline in traumatic cardiac arrest survival

Prehospital epinephrine as a bridge to survival in traumatic cardiac arrest: A nationwide propensity score-matched analysis
The American Journal of Emergency Medicine · Added 27 July 2026

Prehospital epinephrine administration in patients with traumatic cardiac arrest was associated with increased survival to hospital discharge and prehospital ROSC.

Study type

Registry

Design

Nationwide registry propensity score-matched analysis

Participants

22,105 adult traumatic OHCA patients; 807 matched pairs analysed

Main finding

Prehospital adrenaline associated with higher survival to discharge (5.1% vs 2.6%, adjusted OR 1.38, 95% CI 1.36-1.39) and prehospital ROSC (12.8% vs 4.5%, adjusted OR 3.63, 95% CI 2.39-5.51); favourable neurological outcome only after adjustment (OR 1.11)

Caveat

Korean registry, very few patients received adrenaline (3.7%); retrospective design cannot establish causality

Bottom line

Hypothesis-generating

Learning goal

Weigh the role of adrenaline in traumatic cardiac arrest given the limited and uncertain supporting evidence.

More

• Topic: Trauma
• Daily scan: 27 July 2026

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