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Synchronised ventilation faster ROSC in neonatal piglets

Cardiopulmonary resuscitation with synchronized ventilation versus 3:1 compression to ventilation ratio in a neonatal porcine model
Resuscitation Plus · Added 27 July 2026

In a neonatal piglet model of asystolic cardiac arrest, CCSV resulted in a significantly faster time to ROSC compared to 3:1 C:V.

Study type

Simulation

Design

Randomised animal experimental study

Participants

16 neonatal piglets (1-3 days old, 1.8-2.5 kg)

Main finding

Median time to ROSC 61 s (IQR 51-118) with chest compression synchronised ventilation vs 170 s (IQR 105-312) with 3:1 C:V (p=0.030); ROSC rate 7/8 vs 5/8 (p=1.000)

Caveat

Small animal (porcine) model; findings may not translate to human neonatal resuscitation

Bottom line

Hypothesis-generating

Learning goal

Weigh the emerging evidence for chest compression synchronised ventilation against standard ratios in neonatal resuscitation.

More

• Topic: Paediatrics
• Daily scan: 27 July 2026

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