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Operations & systems

Protocol-grounded LLM gave 75% accurate advice

Can a Large Language Model Grounded in Text-Based Agency-Specific Prehospital Protocols Provide Accurate Care Recommendations?
Prehospital Emergency Care · Added 11 May 2026

This study tested whether a large language model trained on agency-specific prehospital protocol documents could generate accurate care recommendations — they found promising accuracy for protocol interpretation and clinical decision support, suggesting potential for LLMs to assist with guideline navigation at the point of care.

Study type
Simulation
Design
Non-human simulation-based experimental evaluation of a RAG-based LLM
Participants
6 clinical scenarios; 169 expected patient care actions
Main finding
The LLM recommended 127 of 169 actions (75%); 5% were 'major misses' (5 of 9 in paediatric OHCA), 8% minor misses, 12% non-applicable; 12 hallucinations identified, none judged to endanger patient safety.
Caveat
Only six scenarios in a single EMS agency; no clinical use or patient outcomes tested
Bottom line
Hypothesis-generating

Learning goal

Understand the risks and safeguards when using AI decision support tools to navigate prehospital protocols at the point of care.

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